The anticoagulant result of warfarin along with other coumarins could possibly be enhanced by prolonged normal every day usage of paracetamol with amplified possibility of bleeding; occasional doses don't have any important impact.
Mix painkillers like co-codamol is usually handy to decrease the whole variety of tablets that have to be taken in each day, but they may not normally give the most beneficial pain Command.
Taking higher doses or maybe more Regular doses of opioid, could enhance the hazard of dependancy. Overuse and misuse can cause overdose and/or Loss of life.
You should inform your doctor or pharmacist Should you be taking or have just lately taken any other medicines, which include These received without a prescription. Ongoing overleaf
For Grown ups and youngsters Over 12: The usual dose is just one to 2 tablets each four to 6 several hours, based on the severity in the pain.
For that reason, concomitant use really should only be considered when other treatment method alternatives are impossible.
Using higher doses or even more frequent doses of opioid, may well increase the threat of habit. Overuse and misuse can cause overdose and/or Loss of life.
Speak with your medical doctor or pharmacist ahead of using opioids. Don't give your medicine to any check here one else. Having higher doses or even more Regular doses of opioid, might increase the chance of addiction. Overuse and misuse can result in overdose and/or death.
If you are pregnant or breast-feeding, Consider you may well be pregnant or are planning to Have a very baby, question your health care provider or pharmacist for suggestions in advance of having this medicine.
Codeine should not be used for pain relief in small children and adolescents just after removing of their tonsils or adenoids as a result of Obstructive Sleep Apnoea Syndrome.
Paracetamol may perhaps enhance the elimination half-life of chloramphenicol. Oral contraceptives may well raise its amount of clearance.
Blood – anaemia, changes in quantities and types of blood cells. If you have a rise in quantity of nose bleeds or notice that you choose to bruise far more effortlessly or have extra bacterial infections speak with your doctor
If you have any side effects, discuss with your medical professional or pharmacist. This involves any attainable side effects not shown In this particular leaflet.
For this reason, concomitant use should only be considered when other cure alternatives are impossible.